A couple of weeks ago, I had the good fortune of catching a webcast from Jeff Prosise of Wintellect entitled:  "Squeeze Your ASP.NET Applications Until They Scream".  I was really impressed with the content and with Jeff's presentation of same.  The event was sponsored by Compuware and they have given me permission to post a link to the presentation. 

Squeeze Your ASP.NET Applications Until They Scream